Metagenomic discovery of novel antimicrobial enzymes from Earth’s extremes

Training course in the life sciences listed on ELIXIR's TeSS training portal, run by European Bioinformatics Institute (EBI), online on 19 January 2027. Bacteriophages, viruses that only infect bacteria, are Earth’s most abundant and diverse biological entities. Their genomes represent the largest untapped source of novel enzymes that function under extreme conditions. Among these, endolysins (phage-encoded peptidoglycan hydrolases) are of huge interest as eco-friendly antimicrobial agents. Topics: Structural biology, Microbiology, Microbial ecology. Adapted from TeSS (CC BY 4.0).