Postdoctoral Research Associate – Biochemistry

Postdoctoral Researcher Position The Ghanbarpour Laboratory in the Department of Biochemistry and Molecular Biophysics at WashU Medicine is seeking a highly motivated Postdoctoral Researcher to join our interdisciplinary research program. Our lab investigates how bacteria and human mitochondria maintain homeostasis and respond to stress and environmental challenges. A central focus of our research is uncovering the molecular mechanisms of ATP-dependent AAA proteolytic machines, both soluble and membrane-spanning, and their accessory factors in bacterial and mitochondrial systems. We study how these complexes assemble, achieve substrate specificity, and promote bacterial recovery from antibiotic stress, environmental changes, and pathogen attack. These efforts combine cryo-EM and cryo-ET structural biology, biochemical and cellular assays, and mass spectrometry.