Postdoctoral Research Associate – Oncology

Postdoctoral Research Fellow A Postdoctoral Research Fellow position is available in Dr. Grant Challen's laboratory in the Division of Oncology at WashU. The Challen lab investigates the epigenetic regulation of normal and malignant hematopoiesis. The successful applicant will be responsible for characterizing the roles of various epigenetic modifications in stem cell differentiation and blood cancer transformation. The project involves understanding the mechanisms by which certain mutations provide stem cells with growth advantages to establish clonal hematopoiesis, and how clonal competition and external stressors drive clonal hematopoiesis towards blood cancer. Our ultimate goal is to identify new points of intervention for therapeutic targeting high-risk clones as a means of blood cancer prevention.