2003 · Nature
Mass spectrometry-based proteomics
6,916 citationsRead
Most cited
1,185 papers in total2002 · Analytical Chemistry
Empirical Statistical Model To Estimate the Accuracy of Peptide Identifications Made by MS/MS and Database Search
4,863 citationsRead
2003 · Analytical Chemistry
A Statistical Model for Identifying Proteins by Tandem Mass Spectrometry
4,833 citationsRead
1999 · Nature Biotechnology
Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
4,684 citationsRead
1999 · Nature
Molecular characterization of mitochondrial apoptosis-inducing factor
4,076 citationsRead
1999 · Molecular and Cellular Biology
Correlation between Protein and mRNA Abundance in Yeast
3,824 citationsRead
Newest first
1,185 papers in total2021
- JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modificationsScience · 243 citations
2020
- diaPASEF: parallel accumulation–serial fragmentation combined with data-independent acquisitionNature Methods · 912 citations
- Proteomic and interactomic insights into the molecular basis of cell functional diversityNature Reviews Molecular Cell Biology · 295 citations
- A high-stringency blueprint of the human proteomeNature Communications · 210 citations
2019
- Multi-omic measurements of heterogeneity in HeLa cells across laboratoriesNature Biotechnology · 340 citations
2018
- Data‐independent acquisition‐based SWATH‐MS for quantitative proteomics: a tutorialMolecular Systems Biology · 1,008 citations
- How many human proteoforms are there?Nature Chemical Biology · 911 citations
- Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complexProceedings of the National Academy of Sciences · 219 citations
2017
- Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometryNature Communications · 572 citations
- Quantitative proteomics: challenges and opportunities in basic and applied researchNature Protocols · 275 citations
- Building ProteomeTools based on a complete synthetic human proteomeNature Methods · 252 citations
- The Human Plasma Proteome Draft of 2017: Building on the Human Plasma PeptideAtlas from Mass Spectrometry and Complementary AssaysJournal of Proteome Research · 234 citations
- Statistical control of peptide and protein error rates in large-scale targeted data-independent acquisition analysesNature Methods · 211 citations
- A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome InstabilityCell · 210 citations
2016
- On the Dependency of Cellular Protein Levels on mRNA AbundanceCell · 3,233 citations
- Mass-spectrometric exploration of proteome structure and functionNature · 2,324 citations
- NAD + repletion improves mitochondrial and stem cell function and enhances life span in miceScience · 1,245 citations
- OpenMS: a flexible open-source software platform for mass spectrometry data analysisNature Methods · 703 citations
- A multicenter study benchmarks software tools for label-free proteome quantificationNature Biotechnology · 353 citations
- Mass Spectrometry Applied to Bottom-Up Proteomics: Entering the High-Throughput Era for Hypothesis TestingAnnual Review of Analytical Chemistry · 326 citations
- Human SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human ProteomeCell · 312 citations
- Systems proteomics of liver mitochondria functionScience · 290 citations
- A High-Density Map for Navigating the Human Polycomb ComplexomeCell Reports · 280 citations
- TRIM24 Is an Oncogenic Transcriptional Activator in Prostate CancerCancer Cell · 265 citations
2015
- The quantitative and condition-dependent Escherichia coli proteomeNature Biotechnology · 780 citations
- A Mass Spectrometric-Derived Cell Surface Protein AtlasPLoS ONE · 444 citations
- The complete structure of the 55 S mammalian mitochondrial ribosomeScience · 398 citations
- Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome mapsNature Medicine · 385 citations
- Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregationNature · 371 citations
- Crosslinking and Mass Spectrometry: An Integrated Technology to Understand the Structure and Function of Molecular MachinesTrends in Biochemical Sciences · 360 citations
Research in numbers
From OpenAlex- article186
- review10
- preprint3
- data paper1
- Molecular & Cellular Proteomics22
- Nature Methods19
- Nature Biotechnology17
- Nature13
- Cell12
- Eric W. Deutsch25
- Jimmy K. Eng17
- Alexander Leitner15
- Robert L. Moritz14
- Alexey I. Nesvizhskii13
Experience and education
Universities
2009Pohang University of Science and Technology
2002University of North Carolina at Chapel Hill
2000West Virginia University
1991 to 1994Dartmouth College
1985 to 1993California Institute of Technology
Industry and labs
2008Broad Institute
2006 to 2007Cedars-Sinai Medical Center
2004Stowers Institute for Medical Research
2002University of British Columbia Hospital
1999New England Biolabs (United States)